Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
- Creator: Shrine, Nick , Izquierdo, Abril G. , Hobbs, Brian D. , Foong, RE , Harris, SE , Taylor, A , Redmond, P , Cook, JP , Mahajan, A , Lind, L , Palviainen, T , Lehtimäki, T , Raitakari, OT , Moll, Matthew , Kaprio, J , Rantanen, T , Pietiläinen, KH , Cox, SR , Pennell, CE , Hall, GL , Gauderman, WJ , Brightling, C , Wilson, JF , Vasankari, T , Kim, Wonji , Laitinen, T , Salomaa, V , Mook-Kanamori, DO , Timpson, NJ , Zeggini, E , Dupuis, J , Hayward, C , Brumpton, B , Langenberg, C , Weiss, S , Tal-Singer, Ruth , Homuth, G , Schmidt, CO , Probst-Hensch, N , Jarvelin, M-R , Morrison, AC , Polasek, O , Rudan, I , Lee, J-H , Sayers, I , Rawlins, EL , Bakke, Per , Dudbridge, F , Silverman, EK , Strachan, DP , Walters, RG , Morris, AP , London, SJ , Cho, MH , Wain, LV , Hall, IP , Tobin, MD , Fawcett, Katherine A. , John, Catherine , Coley, Kayesha , Piga, Noemi Nicole , Pozarickij, Alfred , Chen, Jing , Wang, Carol A. , Pennell, Craig E. , Chen, Z , Li, L , China Kadoorie Biobank Collaborative Group, , Wijnant, SRA , Lahousse, L , Brusselle, G , Uitterlinden, AG , Manichaikul, A , Packer, Richard , Oelsner, EC , Rich, SS , Barr, RG , Kerr, SM , Vitart, V , Brown, MR , Wielscher, M , Imboden, M , Jeong, A , Bartz, TM , Hall, Robert J. , Gharib, SA , Flexeder, C , Karrasch, S , Gieger, C , Peters, A , Stubbe, B , Hu, X , Ortega, VE , Meyers, DA , Bleecker, ER , Guyatt, Anna L. , Gabriel, SB , Gupta, N , Smith, AV , Luan, J , Zhao, J-H , Hansen, AF , Langhammer, A , Willer, C , Bhatta, L , Porteous, D , Batini, Chiara , Smith, BH , Campbell, A , Sofer, T , Lee, J , Daviglus, ML , Yu, B , Lim, E , Xu, H , O'Connor, GT , Thareja, G , Thompson, Rebecca J. , Albagha, OME , Qatar Genome Program Research (QGPR) Consortium, , Suhre, K , Granell, R , Faquih, TO , Hiemstra, PS , Slats, AM , Mullin, BH , Hui, J , James, A , Pavuluri, Chandan , Beilby, J , Patasova, K , Hysi, P , Koskela, JT , Wyss, AB , Jin, J , Sikdar, S , Lee, M , May-Wilson, S , Pirastu, N , Malik, Vidhi , Kentistou, KA , Joshi, PK , Timmers, PRHJ , Williams, AT , Free, RC , Wang, X , Morrison, JL , Gilliland, FD , Wang, CA
- Resource Type: journal article
- Date: 2023
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning
- Creator: Lahti, Jari , Tuominen, Samuli , Boerwinkle, Eric , Bressler, Jan , Campbell, Archie , Campbell, Harry , Chen, Qiang , Corley, Janie , Cox, Simon R. , Davies, Gail , De Jager, Philip L. , Derks, Eske M. , Yang, Qiong , Faul, JD , Fitzpatrick, AL , Fohner, AE , Ford, I , Fornage, M , Gerring, Z , Grabe, HJ , Grodstein, F , Gudnason, V , Simonsick, E , Pergola, Giulio , Holliday, Elizabeth G. , Joshi, PK , Kajantie, E , Kaprio, J , Karell, P , Kleineidam, L , Knol, MJ , Kochan, NA , Kwok, JB , Leber, M , Ahmad, Shahzad , Lam, M , Lee, T , Li, S , Loukola, A , Luck, T , Marioni, RE , Mather, KA , Medland, S , Mirza, SS , Nalls, MA , Amin, Najaf , Nho, K , O’Donnell, A , Oldmeadow, C , Painter, J , Pattie, A , Reppermund, S , Risacher, SL , Rose, RJ , Sadashivaiah, V , Scholz, M , Armstrong, Nicola J. , Satizabal, CL , Schofield, PW , Schraut, KE , Scott, Rodney J. , Simino, J , Smith, AV , Smith, JA , Stott, DJ , Surakka, I , Teumer, A , Beiser, Alexa , Thalamuthu, A , Trompet, S , Turner, ST , van der Lee, SJ , Villringer, A , Völker, U , Wilson, RS , Wittfeld, K , Vuoksimaa, E , Xia, R , Bey, Katharina , Yaffe, K , Yu, L , Zare, H , Zhao, W , Ames, D , Attia, J , Bennett, DA , Brodaty, H , Chasman, DI , Goldman, AL , Bis, Joshua C. , Hayward, C , Ikram, MA , Jukema, JW , Kardia, SLR , Lencz, T , Loeffler, M , Mattay, VS , Palotie, A , Psaty, BM , Ramirez, A
- Resource Type: journal article
- Date: 2022
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
- Creator: Okbay, Aysu , Wu, Yeda , Jiang, Yunxuan , Hicks, Barry , Tian, Chao , Hinds, David A. , Ahlskog, Rafael , Magnusson, Patrik K. E. , Oskarsson, Sven , Hayward, Caroline , Campbell, Archie , Porteous, David J. , Wang, Nancy , Holliday, Elizabeth J. , Scott, Rodney J. , Attia, John R. , Oldmeadow, Christopher , Auton, A , Bell, RK , Bryc, K , Elson, SL , Fontanillas, P , Furlotte, NA , Jayashankar, Hariharan , Hinds, DA , Huber, KE , Kleinman, A , Litterman, NK , McCreight, JC , McIntyre, MH , Mountain, JL , Northover, CAM , Pitts, SJ , Sathirapongsasuti, JF , Bennett, Michael , Sazonova, OV , Shelton, JF , Shringarpure, S , Tung, JY , Vacic, V , Wilson, CH , Fontana, MA , Pers, TH , Rietveld, CA , Chen, GB , Nehzati, Seyed Moeen , Emilsson, V , Meddens, SFW , Pickrell, JK , Thom, K , Timshel, P , de Vlaming, R , Abdellaoui, A , Ahluwalia, TS , Bacelis, J , Baumbach, C , Sidorenko, Julia , Bjornsdottir, G , Brandsma, JH , Concas, MP , Derringer, J , Galesloot, TE , Girotto, G , Gupta, R , Hall, LM , Harris, SE , Hofer, E , Kweon, Hyeokmoon , Horikoshi, M , Huffman, JE , Kaasik, K , Kalafati, IP , Karlsson, R , Lahti, J , van der Lee, SJ , de Leeuw, C , Lind, PA , Lindgren, KO , Goldman, Grant , Liu, T , Mangino, M , Marten, J , Mihailov, E , Miller, MB , van der Most, PJ , Oldmeadow, C , Payton, A , Pervjakova, N , Peyrot, WJ , Gjorgjieva, Tamara , Qian, Y , Raitakari, O , Rueedi, R , Salvi, E , Schmidt, B , Schraut, KE , Shi, J , Smith, AV , Poot, RA , Pourcain, BS
- Resource Type: journal article
- Date: 2022
Associations of autozygosity with a broad range of human phenotypes
- Creator: Clark, David W. , Cocca, M , Collins, FS , Concas, MP , Corley, J , Cugliari, G , Van Dam, RM , Damulina, A , Daneshpour, MS , Day, FR , Delgado, GE , Dhana, K , Doney, ASF , Doerr, M , Doumatey, AP , Dzimiri, N , Ebenesersdottir, SS , Elliott, J , Elliott, P , Ewert, R , Felix, JF , Fischer, K , Freedman, BI , Girotto, G , Goel, A , Gogele, M , Goodarzi, MO , Graff, M , Granot-Hershkovitz, E , Grodstein, F , Guarrera, S , Gudbjartsson, DF , Guity, K , Gunnarsson, B , Guo, Y , Hagenaars, SP , Haiman, CA , Halevy, A , Harris, TB , Hedayati, M , van Heel, DA , Hirata, M , Hofer, I , Hsiung, CA , Huang, J , Hung, Y-J , Ikram, MA , Jagadeesan, A , Jousilahti, P , Kamatani, Y , Kanai, M , Kerrison, ND , Kessler, T , Khaw, K-T , Khor, CC , de Kleijn, DPV , Koh, W-P , Kolcic, I , Kraft, P , Kramer, BK , Kutalik, Z , Kuusisto, J , Langenberg, C , Launer, LJ , Lawlor, DA , Lee, I-T , Lee, W-J , Lerch, MM , Li, L , Liu, J , Loh, M , London, SJ , Loomis, S , Lu, Y , Luan, J , Magi, R , Manichaikul, AW , Manunta, P , Masson, G , Matoba, N , Mei, XW , Meisinger, C , Meitinger, T , Mezzavilla, M , Milani, L , Millwood, IY , Momozawa, Y , Moore, A , Morange, P-E , Moreno-Macias, H , Mori, TA , Morrison, AC , Muka, T , Murakami, Y , Murray, AD , de Mutsert, R , Mychaleckyj, JC , Nalls, MA , Nauck, M , Neville, MJ , Nolte, IM , Ong, KK , Orozco, L , Padmanabhan, S , Palsson, G , Pankow, JS , Pattaro, C , Pattie, A , Polasek, O , Poulter, N , Pramstaller, PP , Quintana-Murci, L , Raikkonen, K , Ralhan, S , Rao, DC , van Rheenen, W , Rich, SS , Ridker, PM , Rietveld, CA , Robino, A , van Rooij, FJA , Ruggiero, D , Saba, Y , Sabanayagam, C , Sabater-Lleal, M , Felicita Sala, C , Salomaa, V , Sandow, K , Schmidt, H , Scott, LJ , Scott, WR , Sedaghati-Khayat, B , Sennblad, B , van Setten, J , Sever, PJ , Sheu, WH-H , Shi, Y , Shrestha, S , Shukla, SR , Sigurdsson, JK , Sikka, TT , Singh, JR , Smith, BH , Stancakova, A , Stanton, A , Starr, JM , Stefansdottir, L , Straker, L , Sulem, P , Sveinbjornsson, G , Swertz, MA , Taylor, AM , Taylor, KD , Terzikhan, N , Tham, Y-C , Thorleifsson, G , Thorsteinsdottir, U , Tillander, A , Tracy, RP , Tusie-Luna, T , Tzoulaki, I , Vaccargiu, S , Vangipurapu, J , Veldink, JH , Vitart, V , Volker, U , Vuoksimaa, E , Wakil, SM , Waldenberger, M , Wander, GS , Wang, YX , Wareham, NJ , Wild, S , Yajnik, CS , Yuan, J-M , Zeng, L , Zhang, L , Zhou, J , Amin, N , Asselbergs, FW , Bakker, SJL , Becker, DM , Lehne, B , Bennett, DA , van den Berg, LH , Berndt, SI , Bharadwaj, D , Bielak, LF , Bochud, M , Boehnke, M , Bouchard, C , Bradfield, JP , Brody, JA , Campbell, A , Carmi, S , Caulfield, MJ , Cesarini, D , Chambers, JC , Chandak, GR , Cheng, C-Y , Ciullo, M , Cornelis, M , Cusi, D , Smith, GD , Deary, IJ , Dorajoo, R , van Duijn, CM , Ellinghaus, D , Erdmann, J , Eriksson, JG , Evangelou, E , Evans, MK , Faul, JD , Feenstra, B , Feitosa, M , Foisy, S , Franke, A , Friedlander, Y , Gasparini, P , Gieger, C , Gonzalez, C , Goyette, P , Grant, SFA , Griffiths, LR , Groop, L , Gudnason, V , Gyllensten, U , Hakonarson, H , Hamsten, A , van der Harst, P , Heng, C-K , Hicks, AA , Hochner, H , Huikuri, H , Hunt, SC , Jaddoe, VWV , De Jager, PL , Johannesson, M , Johansson, A , Jonas, JB , Jukema, JW , Junttila, J , Kaprio, J , Kardia, SLR , Karpe, F , Kumari, M , Laakso, M , van der Laan, SW , Lahti, J , Laudes, M , Lea, RA , Lieb, W , Lumley, T , Martin, NG , Marz, W , Matullo, G , McCarthy, MI , Medland, SE , Merriman, TR , Metspalu, A , Meyer, BF , Mohlke, KL , Montgomery, GW , Mook-Kanamori, D , Munroe, PB , North, KE , Nyholt, DR , O'connell, JR , Ober, C , Oldehinkel, AJ , Palmas, W , Palmer, C , Pasterkamp, GG , Patin, E , Pennell, CE , Perusse, L , Peyser, PA , Pirastu, M , Polderman, TJC , Porteous, DJ , Posthuma, D , Psaty, BM , Rioux, JD , Rivadeneira, F , Rotimi, C , Rotter, JI , Rudan, I , Den Ruijter, HM , Sanghera, DK , Sattar, N , Schmidt, R , Schulze, MB , Schunkert, H , Scott, RA , Shuldiner, AR , Sim, X , Small, N , Smith, JA , Sotoodehnia, N , Tai, E-S , Teumer, A , Timpson, NJ , Toniolo, D , Tregouet, D-A , Tuomi, T , Vollenweider, P , Wang, CA , Weir, DR , Whitfield, JB , Wijmenga, C , Wong, T-Y , Wright, J , Yang, J , Yu, L , Zemel, BS , Zonderman, AB , Perola, M , Magnusson, PKE , Uitterlinden, AG , Kooner, JS , Chasman, DI , Loos, RJF , Franceschini, N , Franke, L , Haley, CS , Hayward, C , Walters, RG , Perry, JRB , Esko, T , Helgason, A , Stefansson, K , Joshi, PK , Kubo, M , Wilson, JF , Okada, Yukinori , Deelen, Patrick , Wang, Carol A. , Pennell, Craig E. , Orozco, Lorena , Rohde, Rebecca , Schurmann, Claudia , Guo, Xiuqing , Giulianini, Franco , Zhang, Weihua , Medina-Gomez, Carolina , Karlsson, Robert , Bao, Yanchun , Bartz, Traci M. , Moore, Kristjan H. S. , Baumbach, Clemens , Biino, G , Bixley, MJ , Brumat, M , Chai, J-F , Corre, T , Cousminer, DL , Dekker, AM , Eccles, DA , Van Eijk, KR , Mason, Dan , Fuchsberger, C , Gao, H , Germain, M , Gordon, SD , de Haan, HG , Harris, SE , Hofer, E , Huerta-Chagoya, A , Igartua, C , Jansen, IE , Pirastu, Nicola , Jia, Y , Kacprowski, T , Karlsson, T , Kleber, ME , Li, SA , Li-Gao, R , Mahajan, A , Matsuda, K , Meidtner, K , Meng, W , Gandin, Ilaria , Montasser, ME , van der Most, PJ , Munz, M , Nutile, T , Palviainen, T , Prasad, G , Prasad, RB , Priyanka, TDS , Rizzi, F , Salvi, E , Mattsson, Hannele , Sapkota, BR , Shriner, D , Skotte, L , Smart, MC , Smith, AV , van der Spek, A , Spracklen, CN , Strawbridge, RJ , Tajuddin, SM , Trompet, S , Barnes, Catriona L. K. , Turman, C , Verweij, N , Viberti, C , Wang, L , Warren, HR , Wootton, RE , Yanek, LR , Yao, J , Yousri, NA , Zhao, W , Lin, Kuang , Adeyemo, AA , Afaq, S , Alberto Aguilar-Salinas, C , Akiyama, M , Albert, ML , Allison, MA , Alver, M , Aung, T , Azizi, F , Bentley, AR , Zhao, Jing Hua , Boeing, H , Boerwinkle, E , Borja, JB , de Borst, GJ , Bottinger, EP , Broer, L , Campbell, H , Chanock, S , Chee, M-L , Chen, G
- Resource Type: journal article
- Date: 2019
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- Creator: Davies, Gail , Lam, Max , Liewald, David C. M. , Knopman, DS , Kochan, NA , Konte, B , Kwok, JB , Le Hellard, S , Lee, T , Lehtimaki, T , Li, S-C , Liu, T , Koini, M , Okely, Judith A. , London, E , Longstreth, WT , Lopez, OL , Loukola, A , Luck, T , Lundervold, AJ , Lundquist, A , Lyytikainen, L-P , Martin, NG , Montgomery, GW , Ahola-Olli, Ari V. , Murray, AD , Need, AC , Noordam, R , Nyberg, L , Ollier, W , Papenberg, G , Pattie, A , Polasek, O , Poldrack, RA , Psaty, BM , Barnes, Catriona L. K. , Reppermund, S , Riedel-Heller, SG , Rose, RJ , Rotter, JI , Roussos, P , Rovio, SP , Saba, Y. , Sabb, FW , Sachdev, PS , Satizabal, CL , Bertram, Lars , Schmid, M , Scott, Rodney J. , Scult, MA , Simino, J , Slagboom, PE , Smyrnis, N , Soumare, A , Stefanis, NC , Stott, DJ , Straub, RE , Bis, Joshua C. , Sundet, K , Taylor, AM , Taylor, KD , Tzoulaki, I , Tzourio, C , Uitterlinden, A , Vitart, V , Voineskos, AN , Kaprio, J , Wagner, M , Burdick, Katherine E. , Wagner, H , Weinhold, L , Wen, KH , Widen, E , Yang, Q , Zhao, W , Adams, HHH , Arking, DE , Bilder, RM , Bitsios, P , Christoforou, Andrea , Boerwinkle, E , Chiba-Falek, O , Corvin, A , De Jager, PL , Debette, S , Donohoe, G , Elliott, P , Fitzpatrick, AL , Gill, M , Glahn, DC , DeRosse, Pamela , Hagg, S , Hansell, NK , Hariri, AR , Ikram, MK , Jukema, JW , Vuoksimaa, E , Keller, MC , Kremen, WS , Launer, L , Lindenberger, U , Djurovic, Srdjan , Palotie, A , Pedersen, NL , Pendleton, N , Porteous, DJ , Raikkonen, K , Raitakari, OT , Ramirez, A , Reinvang, I , Rudan, I , Rujescu, D , Harris, Sarah E. , Espeseth, Thomas , Schmidt, R , Schmidt, H , Schofield, PW , Schofield, PR , Starr, JM , Steen, VM , Trollor, JN , Turner, ST , Van Duijn, CM , Villringer, A , Giakoumaki, Stella , Weinberger, DR , Weir, DR , Wilson, JF , Malhotra, A , McIntosh, AM , Gale, CR , Seshadri, S , Mosley, TH , Bressler, J , Lencz, T , Giddaluru, S , Deary, IJ , Gustavson, DE , Hayward, C , Hofer, E , Ikram, MA , Karlsson, R , Knowles, E , Lahti, J , Trampush, Joey W. , Leber, M , Li, S , Mather, KA , Melle, I , Morris, D , Oldmeadow, Christopher , Palviainen, T , Payton, A , Pazoki, R , Petrovic, K , Luciano, Michelle , Reynolds, CA , Sargurupremraj, M , Scholz, M , Smith, JA , Smith, AV , Terzikhan, N , Thalamuthu, A , Trompet, S , van der Lee, SJ , Ware, EB , Hill, W. David , Windham, BG , Wright, MJ , Yang, J , Yu, J , Ames, D , Amin, N , Amouyel, P , Andreassen, OA , Armstrong, NJ , Assareh, AA , Hagenaars, Saskia P. , Attia, John R. , Attix, D , Avramopoulos, D , Bennett, DA , Boehmer, AC , Boyle, PA , Brodaty, H , Campbell, H , Cannon, TD , Cirulli, ET , Ritchie, Stuart J. , Congdon, E , Conley, ED , Corley, J , Cox, SR , Dale, AM , Dehghan, A , Dick, D , Dickinson, D , Eriksson, JG , Evangelou, E , Marioni, Riccardo E. , Faul, JD , Ford, I , Freimer, NA , Gao, H , Giegling, I , Gillespie, NA , Gordon, SD , Gottesman, RF , Griswold, ME , Gudnason, V , Fawns-Ritchie, Chloe , Harris, TB , Hartmann, AM , Hatzimanolis, A , Heiss, G , Holliday, Elizabeth G. , Joshi, PK , Kahonen, M , Kardia, SLR , Karlsson, I , Kleineidam, L
- Resource Type: journal article
- Date: 2018
1000 genomes-based meta-analysis identifies 10 novel loci for kidney function
- Creator: Gorski, Mathias , van der Most, Peter J. , Li, Yong , Sedaghat, S , Smith, AV , Sorice, R , Stengel, B , Stracke, S , Strauch, K , Toniolo, D , Uitterlinden, AG , Ulivi, S , Viikari, JS , Tayo, Bamidele , Voelker, U , Vollenweider, P , Voelzke, H , Vuckovic, D , Waldenberger, M , Wang, JJ , Yang, Q , Chasman, DI , Tromp, G , Snieder, H , Tin, Adrienne , Heid, IM , Fox, CS , Koettgen, A , Pattaro, C , Boeger, CA , Fuchsberger, C , Feitosa, Mary F. , Aspelund, Thor , Attia, John , Biffar, Reiner , Bochud, Murielle , Boerwinkle, Eric , Borecki, Ingrid , Teumer, Alexander , Bottinger, Erwin P. , Chen, Ming-Huei , Chouraki, Vincent , Ciullo, Marina , Coresh, Josef , Cornelis, Marilyn C. , Curhan, Gary C. , d'Adamo, Adamo P. , Dehghan, Abbas , Dengler, Laura , Chu, Audrey Y. , Ding, Jingzhong , Eiriksdottir, Gudny , Endlich, K , Enroth, S , Esko, T , Franco, OH , Gasparini, P , Gieger, C , Girotto, G , Gottesman, O , Li, Man , Gudnason, V , Gyllensten, U , Hancock, Stephen J. , Harris, TB , Helmer, C , Hoellerer, S , Hofer, E , Hofman, A , Holliday, Elizabeth , Homuth, G , Mijatovic, Vladan , Hu, FB , Huth, C , Hutri-Kahonen, N , Hwang, S-J , Imboden, M , Johansson, A , Kahonen, M , Koenig, W , Kraemer, H , Kramer, BK , Nolte, Ilja M. , Kumar, A , Kutalik, Z , Lambert, J-C , Launer, LJ , Lehtimaki, T , de Borst, M , Navis, G , Swertz, M , Liu, Y , Lohman, K , Cocca, Massimiliano , Loos, RJF , Lu, Y , Lyytikainen, L-P , McEvoy, Mark A. , Meisinger, C , Meitinger, T , Metspalu, A , Metzger, M , Mihailov, E , Mitchell, P , Taliun, Daniel , Nauck, M , Oldehinkel, AJ , Olden, M , Penninx, BWJH , Pistis, G , Pramstaller, PP , Probst-Hensch, N , Raitakari, OT , Rettig, R , Ridker, PM , Gomez, Felicia , Rivadeneira, F , Robino, A , Rosas, SE , Ruderfer, D , Ruggiero, D , Saba, Y. , Sala, C. , Schmidt, H , Schmidt, R , Scott, Rodney J.
- Resource Type: journal article
- Date: 2017